Harper, Mhairi M. and Robertson, Barry and Ricketts, Alastair and Faulds, Karen (2012) Specific detection of DNA through coupling of a TaqMan assay with surface enhanced Raman scattering (SERS). Chemical Communications, 48 (75). pp. 9412-9414. ISSN 1359-7345Full text not available in this repository. (Request a copy from the Strathclyde author)
We have combined the benefits of a TaqMan assay with surface enhanced Raman scattering (SERS), to generate a novel DNA detection method which provides increased sensitivity, with clear applications for disease identification through clinical testing. Target DNA detection limits by SERS were shown to be lower than conventional fluorescence detection and clinically relevant samples of methicillin-resistant Staphylococcus aureus were detected with high specificity.
|Keywords:||surface enhanced Raman scattering , DNA , TaqMan assay , SERS, Physical and theoretical chemistry|
|Subjects:||Science > Chemistry > Physical and theoretical chemistry|
|Department:||Faculty of Science > Pure and Applied Chemistry|
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|Depositing user:||Pure Administrator|
|Date Deposited:||16 Oct 2012 12:59|
|Last modified:||12 Jun 2013 14:34|
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