Specific detection of DNA through coupling of a TaqMan assay with surface enhanced Raman scattering (SERS)

Harper, Mhairi M. and Robertson, Barry and Ricketts, Alastair and Faulds, Karen (2012) Specific detection of DNA through coupling of a TaqMan assay with surface enhanced Raman scattering (SERS). Chemical Communications, 48 (75). pp. 9412-9414. ISSN 1359-7345 (https://doi.org/10.1039/c2cc34859d)

Abstract

We have combined the benefits of a TaqMan assay with surface enhanced Raman scattering (SERS), to generate a novel DNA detection method which provides increased sensitivity, with clear applications for disease identification through clinical testing. Target DNA detection limits by SERS were shown to be lower than conventional fluorescence detection and clinically relevant samples of methicillin-resistant Staphylococcus aureus were detected with high specificity.

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• Item metadata

  Item type:	Article
  ID code:	41480
  Dates:	Date Event 2012 Published
  Subjects:	Science > Chemistry > Physical and theoretical chemistry
  Department:	Faculty of Science > Pure and Applied Chemistry Technology and Innovation Centre > Bionanotechnology
  Depositing user:	Pure Administrator
  Date deposited:	16 Oct 2012 11:59
  Last modified:	08 Apr 2024 20:10
  Related URLs:	Scopus publication
  URI:	https://strathprints.strath.ac.uk/id/eprint/41480