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Acute B-type natriuretic peptide response and early postoperative right ventricular physiology following tetralogy of Fallot's repair

Peng, Edward W K and Spooner, Richard and Young, David and Danton, Mark H D (2012) Acute B-type natriuretic peptide response and early postoperative right ventricular physiology following tetralogy of Fallot's repair. Interactive Cardiovascular and Thoracic Surgery, 15 (3). pp. 335-339.

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Abstract

B-type natriuretic peptide (BNP) response early after a tetralogy of Fallot's repair remains unclear. BNP was measured pre- and post-operatively (immediately, day 1) in 18 children undergoing corrective repair with concurrent echocardiography (pre-, post-op day 1) to assess right ventricular (RV) systolic dysfunction, restrictive physiology, wall motion and pulmonary regurgitation (PR). In the first 24 h postoperatively, BNP rose acutely in all patients (mean 34.9 vs 144.4 vs 716.9 pg/ml at pre-op, days 0 and 1; P