MacMillan, Donna Stephanie and Murray, Jane and Sneddon, Helen F. and Jamieson, Craig and Watson, Allan (2012) Replacement of dichloromethane within chromatographic purification : a guide to alternative solvents. Green Chemistry, 14 (11). pp. 3016-3019. ISSN 1463-9262
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Official URL: http://dx.doi.org/10.1039/C2GC36378J
Abstract
Replacement of dichloromethane as the bulk medium within chromatographic purification has been evaluated with a broad range of molecules containing functionality common within Medicinal Chemistry programmes. Analysis of the data set has generated a set of general guidelines to assist in the selection of alternative solvents for CH2Cl2 as the bulk media in these ubiquitously employed processes.
| Item type: | Article |
|---|---|
| ID code: | 41364 |
| Keywords: | green chemistry, purification, alternative solvents, chromatography , replacement, dichloromethane , chromatographic purification , Chemistry |
| Subjects: | Science > Chemistry |
| Department: | Faculty of Science > Pure and Applied Chemistry |
| Related URLs: | |
| Depositing user: | Pure Administrator |
| Date Deposited: | 09 Oct 2012 11:59 |
| Last modified: | 27 Jan 2013 16:47 |
| URI: | http://strathprints.strath.ac.uk/id/eprint/41364 |
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