Strathprints logo
Strathprints Home | Open Access | Browse | Search | User area | Copyright | Help | Library Home | SUPrimo

Replacement of dichloromethane within chromatographic purification : a guide to alternative solvents

MacMillan, Donna Stephanie and Murray, Jane and Sneddon, Helen F. and Jamieson, Craig and Watson, Allan (2012) Replacement of dichloromethane within chromatographic purification : a guide to alternative solvents. Green Chemistry, 14 (11). pp. 3016-3019. ISSN 1463-9262

[img]
Preview
PDF - Published Version
Available under License ["licenses_description_unspecified" not defined].

Download (640Kb) | Preview

    Abstract

    Replacement of dichloromethane as the bulk medium within chromatographic purification has been evaluated with a broad range of molecules containing functionality common within Medicinal Chemistry programmes. Analysis of the data set has generated a set of general guidelines to assist in the selection of alternative solvents for CH2Cl2 as the bulk media in these ubiquitously employed processes.

    Item type: Article
    ID code: 41364
    Keywords: green chemistry, purification, alternative solvents, chromatography , replacement, dichloromethane , chromatographic purification , Chemistry, Environmental Chemistry, Pollution
    Subjects: Science > Chemistry
    Department: Faculty of Science > Pure and Applied Chemistry
    Related URLs:
      Depositing user: Pure Administrator
      Date Deposited: 09 Oct 2012 11:59
      Last modified: 27 Mar 2014 11:02
      URI: http://strathprints.strath.ac.uk/id/eprint/41364

      Actions (login required)

      View Item

      Fulltext Downloads: