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The Strathprints institutional repository is a digital archive of University of Strathclyde's Open Access research outputs. Strathprints provides access to thousands of Open Access research papers by Strathclyde researchers, including by researchers from the Physical Activity for Health Group based within the School of Psychological Sciences & Health. Research here seeks to better understand how and why physical activity improves health, gain a better understanding of the amount, intensity, and type of physical activity needed for health benefits, and evaluate the effect of interventions to promote physical activity.

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Glucose uptake stimulatory effect of akuammicine from picralima nitida (Apocynaceae)

Shittu, H and Gray, Alexander and Furman, Brian and Young, Louise (2010) Glucose uptake stimulatory effect of akuammicine from picralima nitida (Apocynaceae). Phytochemistry Letters, 3 (1). pp. 53-55.

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Abstract

A bioactivity-guided fractionation of the chloroform extract of the seeds of Picralima nitida using glucose uptake in fully differentiated 3T3-L1 adipocytes afforded six indole alkaloids (akuammicine, 10-deoxyakuammine, akuammine, akuammidine, burnamine and picraline) and a mixture of four 5-hydroxy tryptamine amides. Akuammicine accounted for the increase in glucose uptake observed in the chloroform extract. (C) 2009 Phytochemical Society of Europe.