Rotondo, D and Davidson, Jillian (2012) Genetics and molecular biology : the role of nucleotide oligomerization domain-like genes in insulin resistance. Current Opinion in Lipidology, 23 (5). pp. 501-502. ISSN 0957-9672Full text not available in this repository. (Request a copy from the Strathclyde author)
Insulin resistance is linked to altered fat metabolism and elevated expression of inflammatory cytokines, particularly from fat tissue. This is turn is associated with obesity. It is proposed that NOD-like receptor expression may be responsible for inducing cytokine production from innate immune cells such as macrophages in fat tissue which in turn are linked to insulin resistance and obesity.
|Keywords:||insulin resistance, NOD-like receptors, inflammatory cytokines, macrophages, obesity , genetics, molecular biology, nucleotide oligomerization , domain-like genes, Pharmacy and materia medica, Cell Biology, Genetics, Endocrinology, Diabetes and Metabolism, Molecular Biology, Cardiology and Cardiovascular Medicine, Nutrition and Dietetics|
|Subjects:||Medicine > Pharmacy and materia medica|
|Department:||Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences|
|Depositing user:||Pure Administrator|
|Date Deposited:||17 Sep 2012 13:28|
|Last modified:||07 Jan 2017 07:58|