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Open Access research that challenges the mind...

The Strathprints institutional repository is a digital archive of University of Strathclyde research outputs. Strathprints provides access to thousands of Open Access research papers by University of Strathclyde researchers, including those from the School of Psychological Sciences & Health - but also papers by researchers based within the Faculties of Science, Engineering, Humanities & Social Sciences, and from the Strathclyde Business School.

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Genetics and molecular biology : the role of nucleotide oligomerization domain-like genes in insulin resistance

Rotondo, D and Davidson, Jillian (2012) Genetics and molecular biology : the role of nucleotide oligomerization domain-like genes in insulin resistance. Current Opinion in Lipidology, 23 (5). pp. 501-502. ISSN 0957-9672

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Abstract

Insulin resistance is linked to altered fat metabolism and elevated expression of inflammatory cytokines, particularly from fat tissue. This is turn is associated with obesity. It is proposed that NOD-like receptor expression may be responsible for inducing cytokine production from innate immune cells such as macrophages in fat tissue which in turn are linked to insulin resistance and obesity.