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Open Access research with a real impact on health...

The Strathprints institutional repository is a digital archive of University of Strathclyde's Open Access research outputs. Strathprints provides access to thousands of Open Access research papers by Strathclyde researchers, including by researchers from the Physical Activity for Health Group based within the School of Psychological Sciences & Health. Research here seeks to better understand how and why physical activity improves health, gain a better understanding of the amount, intensity, and type of physical activity needed for health benefits, and evaluate the effect of interventions to promote physical activity.

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Genetics and molecular biology : the role of nucleotide oligomerization domain-like genes in insulin resistance

Rotondo, D and Davidson, Jillian (2012) Genetics and molecular biology : the role of nucleotide oligomerization domain-like genes in insulin resistance. Current Opinion in Lipidology, 23 (5). pp. 501-502. ISSN 0957-9672

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Abstract

Insulin resistance is linked to altered fat metabolism and elevated expression of inflammatory cytokines, particularly from fat tissue. This is turn is associated with obesity. It is proposed that NOD-like receptor expression may be responsible for inducing cytokine production from innate immune cells such as macrophages in fat tissue which in turn are linked to insulin resistance and obesity.