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A comparison of stochastic variation in mixed and unmixed casework and synthetic samples

Bright, J. A. and McManus, K. and Harbison, S. and Gill, Peter and Buckleton, J. (2012) A comparison of stochastic variation in mixed and unmixed casework and synthetic samples. Forensic Science International: Genetics, 6 (2). pp. 180-184. ISSN 1872-4973

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Abstract

Understanding the behaviour of mixed DNA profiles is of paramount importance in forensic DNA analysis. Key parameters are those of heterozygote balance and mixture proportion and its variability. These parameters have been previously explored as a function of the average peak height of the active alleles in single source and mixed samples derived from pristine DNA. Here we report a comparison of this data with data obtained from casework samples. This allows an assessment of the difference in the distribution of heterozygote balance between mixed and single source stains and between casework mixtures and synthetic mixtures constructed from pristine DNA.

Item type: Article
ID code: 40261
Keywords: mixture proportion, mixed DNA profile, heterozygote balance, STR mixtures, Chemistry, Genetics, Pathology and Forensic Medicine
Subjects: Science > Chemistry
Department: Faculty of Science > Pure and Applied Chemistry
Related URLs:
Depositing user: Pure Administrator
Date Deposited: 29 Jun 2012 12:53
Last modified: 27 Mar 2014 10:14
URI: http://strathprints.strath.ac.uk/id/eprint/40261

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