Picture of person typing on laptop with programming code visible on the laptop screen

World class computing and information science research at Strathclyde...

The Strathprints institutional repository is a digital archive of University of Strathclyde's Open Access research outputs. Strathprints provides access to thousands of Open Access research papers by University of Strathclyde researchers, including by researchers from the Department of Computer & Information Sciences involved in mathematically structured programming, similarity and metric search, computer security, software systems, combinatronics and digital health.

The Department also includes the iSchool Research Group, which performs leading research into socio-technical phenomena and topics such as information retrieval and information seeking behaviour.

Explore

Simultaneous patch-clamp and photometric fluorescence ratio measurements of optical probes for ions using a computer-based data acquisition system, PhoCal

Somasundaram, B. and Hoyland, J. and Dempster, John and Riley, J. and Mason, W.T. (1992) Simultaneous patch-clamp and photometric fluorescence ratio measurements of optical probes for ions using a computer-based data acquisition system, PhoCal. Journal of Physiology, 446 (Suppl.). P63-P63. ISSN 0022-3751

Full text not available in this repository. Request a copy from the Strathclyde author

Abstract

This demonstration will present a new computer program and analytical system - PhoCal - which permits the simultaneous measurement of (a) low light levels of fluorescence from optical probes for ions and (b) up to two channels of physiological data which can include patch-clamp current and voltage, or voltage from other probes such as extracellular pH electrodes or other transducers and (c) an event marker channel. The system is PC-based and uses high speed analogto-digital circuitry operating in parallel with a two-channel photon counter which collects data from one or two photomultiplier tubes. All data is logged directly to hard disk and the system can operate at speeds in excess of an aggregate of 1000 samples per second.