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The Strathprints institutional repository is a digital archive of University of Strathclyde's Open Access research outputs. Strathprints provides access to thousands of Open Access research papers by Strathclyde researchers, including by researchers from the Physical Activity for Health Group based within the School of Psychological Sciences & Health. Research here seeks to better understand how and why physical activity improves health, gain a better understanding of the amount, intensity, and type of physical activity needed for health benefits, and evaluate the effect of interventions to promote physical activity.

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Efficacy in vivo of a cancer therapy strategy combining HSV1716 mediated oncolysis with gene transfer and targeted radiotherapy

Sorensen, Annette and Mairs, Robert J. and Braidwood, Lynne and Joyce, Craig and Conner, Joe and Pimlott, Sally and Brown, S. Moira and Boyd, Marie (2012) Efficacy in vivo of a cancer therapy strategy combining HSV1716 mediated oncolysis with gene transfer and targeted radiotherapy. Mutagenesis, 27 (1). pp. 134-135. ISSN 0267-8357

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Abstract

Oncolytic herpes viruses have show promise for the treatment of cancer however it is unlikely that the optimal application of these viruses will be as single therapeutic agents. An alternative strategy would be to utilise these viruses to deliver therapeutic transgenes and enhance their tumour cell killing capacity.