McCluskey, A. G. and Mairs, R. J. and Robson, T. and Hirst, D. G. and Boyd, M. (2012) Activation of the noradrenaline transporter gene using the radiation-inducible WAF1-1 promoter sensitizes tumour cells to [I-131] MIBG targeted radiotherapy. Mutagenesis, 27 (1). p. 131. ISSN 0267-8357
Full text not available in this repository. (Request a copy from the Strathclyde author)Official URL: http://dx.doi.org/10.1093/mutage/ger068
Abstract
Radiotherapy given in combination with gene transfer is a promising approach for the treatment of cancer. However, progress in this field depends upon achieving the selective expression of therapeutic transgenes in tumours. Therefore, radiation-inducible gene promoters have attracted interest because they may enable temporal and spatial gene activation.
| Item type: | Article |
|---|---|
| ID code: | 40162 |
| Keywords: | noradrenaline transporter, radiotherapy, Pharmacy and materia medica |
| Subjects: | Medicine > Pharmacy and materia medica |
| Department: | Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences |
| Related URLs: | |
| Depositing user: | Pure Administrator |
| Date Deposited: | 22 Jun 2012 09:29 |
| Last modified: | 10 Apr 2013 10:36 |
| URI: | http://strathprints.strath.ac.uk/id/eprint/40162 |
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