Olson, Marnie L and Chalmers, Susan and McCarron, John G (2012) Mitochondrial organization and Ca2+ uptake. Biochemical Society Transactions, 40 (1). pp. 158-167.Full text not available in this repository. (Request a copy from the Strathclyde author)
Mitochondria may function as multiple separate organelles or as a single electrically coupled continuum to modulate changes in [Ca2+]c (cytoplasmic Ca2+ concentration) in various cell types. Mitochondria may also be tethered to the internal Ca2+ store or plasma membrane in particular parts of cells to facilitate the organelles modulation of local and global [Ca2+]c increases. Differences in the organization and positioning contributes significantly to the at times apparently contradictory reports on the way mitochondria modulate [Ca2+]c signals. In the present paper, we review the organization of mitochondria and the organelles role in Ca2+ signalling.
|Keywords:||cell types, Mitochondria , Ca2+, Pharmacy and materia medica, Biochemistry|
|Subjects:||Medicine > Pharmacy and materia medica|
|Department:||Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences|
|Depositing user:||Pure Administrator|
|Date Deposited:||14 Jun 2012 12:15|
|Last modified:||27 Apr 2016 18:39|