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Mitochondrial organization and Ca2+ uptake

Olson, Marnie L and Chalmers, Susan and McCarron, John G (2012) Mitochondrial organization and Ca2+ uptake. Biochemical Society Transactions, 40 (1). pp. 158-167.

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Abstract

Mitochondria may function as multiple separate organelles or as a single electrically coupled continuum to modulate changes in [Ca2+]c (cytoplasmic Ca2+ concentration) in various cell types. Mitochondria may also be tethered to the internal Ca2+ store or plasma membrane in particular parts of cells to facilitate the organelles modulation of local and global [Ca2+]c increases. Differences in the organization and positioning contributes significantly to the at times apparently contradictory reports on the way mitochondria modulate [Ca2+]c signals. In the present paper, we review the organization of mitochondria and the organelles role in Ca2+ signalling.

Item type: Article
ID code: 40051
Keywords: cell types, Mitochondria , Ca2+, Pharmacy and materia medica, Biochemistry
Subjects: Medicine > Pharmacy and materia medica
Department: Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
Related URLs:
Depositing user: Pure Administrator
Date Deposited: 14 Jun 2012 13:15
Last modified: 27 Mar 2014 10:11
URI: http://strathprints.strath.ac.uk/id/eprint/40051

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