Olson, Marnie L and Chalmers, Susan and McCarron, John G (2012) Mitochondrial organization and Ca2+ uptake. Biochemical Society Transactions, 40 (1). pp. 158-167.
Full text not available in this repository. (Request a copy from the Strathclyde author)Abstract
Mitochondria may function as multiple separate organelles or as a single electrically coupled continuum to modulate changes in [Ca2+]c (cytoplasmic Ca2+ concentration) in various cell types. Mitochondria may also be tethered to the internal Ca2+ store or plasma membrane in particular parts of cells to facilitate the organelles modulation of local and global [Ca2+]c increases. Differences in the organization and positioning contributes significantly to the at times apparently contradictory reports on the way mitochondria modulate [Ca2+]c signals. In the present paper, we review the organization of mitochondria and the organelles role in Ca2+ signalling.
| Item type: | Article |
|---|---|
| ID code: | 40051 |
| Keywords: | cell types, Mitochondria , Ca2+, Pharmacy and materia medica |
| Subjects: | Medicine > Pharmacy and materia medica |
| Department: | Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences |
| Related URLs: | |
| Depositing user: | Pure Administrator |
| Date Deposited: | 14 Jun 2012 13:15 |
| Last modified: | 14 Jun 2012 13:15 |
| URI: | http://strathprints.strath.ac.uk/id/eprint/40051 |
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