Dufès, Christine (2011) Targeted dendrimers. A61K 47/48.Full text not available in this repository. (Request a copy from the Strathclyde author)
The present invention relates to a composition for targeted delivery of a bioactive molecule to cells in a body of a recipient, said composition comprising a polypropylenimine dendrimer and/or derivatives thereof to which one or more cell targeting molecule (s) have been conjugated thereto; and a bioactive molecule associated with said polypropylenimine dendrimer and/or derivative thereof. In one embodiment the cells to be targeted are cancer cells. The targeting molecule may be transferrin, lactoferrin, lactoferricin or gambogic acid. There is also provided uses of such compositions, as well as methods of treating diseases, such as cancer.
|Keywords:||bioactive molecule, polypropylenimine dendrimer, cell targeting, cancer cells, Therapeutics. Pharmacology|
|Subjects:||Medicine > Therapeutics. Pharmacology|
|Department:||Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences|
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|Depositing user:||Pure Administrator|
|Date Deposited:||16 May 2012 11:50|
|Last modified:||12 Jun 2013 14:35|
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