Garayt, Maxime R and Percy, Jonathan (2001) A direct and useful route to difluoroacylsilanes and difluoroacylstannanes and their potential for the generation of structurally diverse difluoroketones. Tetrahedron Letters, 42 (36). pp. 6377-6380. ISSN 0040-4039Full text not available in this repository. (Request a copy from the Strathclyde author)
Allyl trifluoroethyl ethers 2a–2d were prepared; each underwent efficient dehydrofluorination/metallation and trapping to afford a range of difluoroenol silanes and stannanes which rearranged easily and efficiently to the acyl metals. Fluoride-mediated benzylation and allylation of an acylsilane, and Stille coupling of the vinyl- and acyl-stannane were achieved in moderate to good yield.
|Keywords:||dehydrofluorination, metallation, difluoroenol silanes, Allyl trifluoroethyl ethers , Chemistry, Biochemistry, Organic Chemistry, Drug Discovery|
|Subjects:||Science > Chemistry|
|Department:||Faculty of Science > Pure and Applied Chemistry|
|Depositing user:||Pure Administrator|
|Date Deposited:||04 Apr 2012 10:53|
|Last modified:||07 Jan 2017 01:05|