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Synthesis of cis,cis-diunsaturated α-meromycolic acid by a palladium-catalysed alkyl–alkyl Negishi reaction

Berretta, Giacomo and Coxon, Geoffrey (2012) Synthesis of cis,cis-diunsaturated α-meromycolic acid by a palladium-catalysed alkyl–alkyl Negishi reaction. Tetrahedron Letters, 53 (2). pp. 214-216. ISSN 0040-4039

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Abstract

The first total synthesis of cis,cis-diunsaturated α-meromycolic acid has been accomplished using a convergent strategy and a palladium-catalysed alkyl–alkyl Negishi reaction as the key step.

Item type: Article
ID code: 38937
Keywords: fatty acids, Negishi reaction, synthesis, tuberculosis, drug discovery, mycolic acids, meromycolate, Pharmacy and materia medica, Biochemistry, Organic Chemistry, Drug Discovery
Subjects: Medicine > Pharmacy and materia medica
Department: Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
Related URLs:
    Depositing user: Pure Administrator
    Date Deposited: 04 Apr 2012 11:14
    Last modified: 05 Sep 2014 15:40
    URI: http://strathprints.strath.ac.uk/id/eprint/38937

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