Picture of person typing on laptop with programming code visible on the laptop screen

World class computing and information science research at Strathclyde...

The Strathprints institutional repository is a digital archive of University of Strathclyde's Open Access research outputs. Strathprints provides access to thousands of Open Access research papers by University of Strathclyde researchers, including by researchers from the Department of Computer & Information Sciences involved in mathematically structured programming, similarity and metric search, computer security, software systems, combinatronics and digital health.

The Department also includes the iSchool Research Group, which performs leading research into socio-technical phenomena and topics such as information retrieval and information seeking behaviour.

Explore

Synthesis, full chemical characterisation and development of validated methods for the quantification of the components found in the evolved “legal high” NRG-2

Khreit, Osama I. G. and Irving, Craig and Schmidt, Elke and Parkinson, John A. and Daeid, Niamh Nic and Sutcliffe, Oliver B. (2012) Synthesis, full chemical characterisation and development of validated methods for the quantification of the components found in the evolved “legal high” NRG-2. Journal of Pharmaceutical and Biomedical Analysis, 61. pp. 122-135. ISSN 0731-7085

Full text not available in this repository. Request a copy from the Strathclyde author

Abstract

The recent global increase in the abuse of 4-methylmethcathinone (mephedrone) and related compounds has developed a requirement for full chemical characterisation of these products. This work presents full synthetic and chemical characterisation data for the hydrobromide salts of two mephedrone derivatives: 4-methyl-N-ethylcathinone (4-MEC) and 4-methyl-N-benzylcathinone (4-MBC) which have been identified in samples of the “legal high” NRG-2. The first fully validated chromatographic methods for the detection and quantitative analysis of these substances both in their pure form and in the presence of a number of common adulterants used in illicit drug manufacture is also reported.