A powerful palladium-catalyzed multicomponent process for the preparation of oxazolines and benzoxazoles

Boissarie, Patrick and Hamilton, Zoe and Lang, Stuart and Murphy, John and Suckling, Colin (2011) A powerful palladium-catalyzed multicomponent process for the preparation of oxazolines and benzoxazoles. Organic Letters, 13 (23). pp. 6256-6259. ISSN 1523-7060 (https://doi.org/10.1021/ol202725y)

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Abstract

Efficient and convenient three-component couplings of an aryl halide, isocyanide, and an amino alcohol under palladium catalysis provide a range of oxazolines and benzoxazoles in excellent yield.