Picture of virus under microscope

Research under the microscope...

The Strathprints institutional repository is a digital archive of University of Strathclyde research outputs.

Strathprints serves world leading Open Access research by the University of Strathclyde, including research by the Strathclyde Institute of Pharmacy and Biomedical Sciences (SIPBS), where research centres such as the Industrial Biotechnology Innovation Centre (IBioIC), the Cancer Research UK Formulation Unit, SeaBioTech and the Centre for Biophotonics are based.

Explore SIPBS research

Development of an anatomical carotid artery flow phantom for the calibration of doppler ultrasound systems

Watts, D.M. and Sutcliffe, C.J. and Morgan, R.H. and Black, R.A. and Meagher, S. and Wardlaw, J. and Connel, M and Hoskins, P. (2003) Development of an anatomical carotid artery flow phantom for the calibration of doppler ultrasound systems. In: 4th National Conference on Rapid and Virtual Prototyping and Applications, 2003-06-19 - 2003-06-20.

Full text not available in this repository. (Request a copy from the Strathclyde author)

Abstract

Cardiovascular diseases are responsible for over 50% of all deaths in the UK. Current measurement techniques involve non-invasive Doppler ultrasound imaging of blood velocity, however it is known that measured velocity may be in error by typically 20-60%. This paper presents the development of anatomically correct tissue equivalent vessels for calibration of Doppler ultrasound by particle imaging techniques. Patient specific arterial MRI data is used as the basis for construction of a 3D CAD model. The model was modified to simulate varying degrees of stenosis (narrowing). The arterial geometry is fabricated by Stereolithography to generate investment cast patterns from low melting point alloy. The expendable cores are then used in the construction of optically transparent models for particle image velocimetry (PIV) analysis and for agar models using an acoustically matched tissue mimic material for Doppler ultrasound measurement. Issues concerning the fabrication of models for direct comparison of Doppler and PIV data will be discussed.