Katerere, D.R. and Gray, A. and Nash, R.J. and Waigh, R.D. (2003) Antimicrobial activity of pentacyclic triterpenes isolated from African combretaceae. Phytochemistry, 63 (1). pp. 81-99. ISSN 0031-9422Full text not available in this repository. (Request a copy from the Strathclyde author)
Four pentacyclic tritepenes were isolated from Combretum imberbe Engl. & Diels, of which two are novel glycosidic derivatives of 1α,3β,23-trihydroxyolean-12-en-29-oic acid (hydroxyimberbic acid). Terminalia stuhlmannii Engl. & Diels stem bark yielded two glycosides of hydroxyimberbic acid, one of which is reported for the first time. The structures of the isolated compounds were elucidated by spectroscopic methods. Several of the compounds had antibacterial activity, imberbic acid showing particularly potent activity against Mycobacterium fortuitum and Staphylococcus aureus.
|Keywords:||pentacyclic tritepenes , novel glycosidic derivatives , spectroscopic methods , Staphylococcus aureus, Pharmacy and materia medica, Plant Science, Biochemistry, Horticulture, Molecular Biology|
|Subjects:||Medicine > Pharmacy and materia medica|
|Department:||Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences|
|Depositing user:||Pure Administrator|
|Date Deposited:||12 Mar 2012 15:10|
|Last modified:||12 Aug 2016 02:21|