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Towards a systems understanding of the cerebral motor circuit

Wellstead, P. and Mason, O. and O'Connor, W.T. and Cho, K. and Bullinger, Eric and Wolkenhauer, O. and Duncan, S. (2005) Towards a systems understanding of the cerebral motor circuit. In: 1st International Conference on Foundations of Systems Biology in Engineering, 2005-08-07 - 2005-08-10.

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The objectives of this programme were to apply ideas from dynamical systems modelling to build a unified understanding of Parkinson’s Disease In this study we look specifically at the indirect part of cerebral motor circuit and examine the actions of full and partial Dopamine agonists.