Picture of person typing on laptop with programming code visible on the laptop screen

World class computing and information science research at Strathclyde...

The Strathprints institutional repository is a digital archive of University of Strathclyde's Open Access research outputs. Strathprints provides access to thousands of Open Access research papers by University of Strathclyde researchers, including by researchers from the Department of Computer & Information Sciences involved in mathematically structured programming, similarity and metric search, computer security, software systems, combinatronics and digital health.

The Department also includes the iSchool Research Group, which performs leading research into socio-technical phenomena and topics such as information retrieval and information seeking behaviour.

Explore

The toxicity of troglitazone, roziglitazone and vitamin e in human hep g2 hepatoma cells

Ball, A.J. and Tettey, J.N.A. and Grant, M.H. (2004) The toxicity of troglitazone, roziglitazone and vitamin e in human hep g2 hepatoma cells. Toxicology, 194 (3). pp. 250-251. ISSN 0300-483X

Full text not available in this repository. Request a copy from the Strathclyde author

Abstract

Troglitazone (TGZ), a member of the thiazolidinedione class of drugs used to treat type-II diabetes, has been associated with hepatotoxicity (Biswas et al., 2001). TGZ differs structurally from the newer non-hepatotoxic glitazone, rosiglitazone (RGZ), in that it contains the chromanol moiety of Vitamin E (Vit E). This study compares the toxicity of TGZ, RGZ and Vit E in human HepG2 cells