System analysis of a programmed cell death model

Bullinger, Eric (2006) System analysis of a programmed cell death model. In: 44th IEEE Conference on Decision and Control and European Control Conference, 2005-12-12 - 2005-12-15. (https://doi.org/10.1109/CDC.2005.1583455)

Abstract

Apoptosis is a programmed cell death by which the organism removes unwanted cells. Its core reactions can be described by a system of differential equations exhibiting multiple steady-states. In this paper we analyse how this model can include both very slow dynamics for the lag phase before apoptosis (in theory up to several days) while the apoptosis itself is more switch-like with changes occurring within minutes. We both describe how the trajectories evolve during the lag phase and show which of the states have the most impact on the slow dynamics.

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• Item metadata

  Item type:	Conference or Workshop Item(Paper)
  ID code:	37584
  Dates:	Date Event 2006 Published
  Subjects:	Technology > Electrical engineering. Electronics Nuclear engineering
  Department:	Faculty of Engineering > Electronic and Electrical Engineering
  Depositing user:	Pure Administrator
  Date deposited:	10 Feb 2012 16:21
  Last modified:	09 Apr 2024 05:14
  URI:	https://strathprints.strath.ac.uk/id/eprint/37584