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The Strathprints institutional repository is a digital archive of University of Strathclyde research outputs.

Strathprints serves world leading Open Access research by the University of Strathclyde, including research by the Strathclyde Institute of Pharmacy and Biomedical Sciences (SIPBS), where research centres such as the Industrial Biotechnology Innovation Centre (IBioIC), the Cancer Research UK Formulation Unit, SeaBioTech and the Centre for Biophotonics are based.

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A novel white matter fibre tracking algorithm using probabilistic tractography and average curves.

Ratnarajah, Nagulan and Simmons, Andrew and Davydov, Oleg and Hojjatoleslami, Ali (2010) A novel white matter fibre tracking algorithm using probabilistic tractography and average curves. In: Med Image Comput Comput Assist Interv - MICCAI 2010, 2010-09-20.

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Abstract

This paper presents a novel white matter fibre tractography approach using average curves of probabilistic fibre tracking measures. We compute "representative" curves from the original probabilistic curve-set using two different averaging methods. These typical curves overcome a number of the limitations of deterministic and probabilistic approaches. They produce strong connections to every anatomically distinct fibre tract from a seed point and also convey important information about the underlying probability distribution. A new clustering algorithm is employed to separate fibres into branches before applying averaging methods. The performance of the technique is verified on a wide range of seed points using a phantom dataset and an in vivo dataset.