Mccarron, John and Bradley, Karen and Macmillan, Debbi and Chalmers, Susan and Muir, Thomas C. (2004) The sarcoplasmic reticulum, Ca2+ trapping, and wave mechanisms in smooth muscle. News in Physiological Sciences, 19. pp. 138-147. ISSN 0886-1714
Full text not available in this repository. (Request a copy from the Strathclyde author)Official URL: http://dx.doi.org/10.1152/nips.01518.2004
Abstract
The sarcoplasmic reticulum (SR) and apposed regions of the sarcolemma passively trap Ca2+ entering the cell to limit the rise in cytoplasmic Ca2+ concentration without SR pump involvement. When "leaky," the SR facilitates Ca2+ entry to the cytoplasm. SR Ca2+ release via inositol 1,4,5-trisphosphate receptors (IP(3)Rs) propagates as calcium waves; IP(3)Rs alone account for wave propagation.
| Item type: | Article |
|---|---|
| ID code: | 36041 |
| Keywords: | inositol 1,4,5-trisphosphate receptors, cells, oscillations, induced calcium-release, Pharmacy and materia medica |
| Subjects: | Medicine > Pharmacy and materia medica |
| Department: | Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences Faculty of Science > Physiology & Pharmacology |
| Related URLs: | |
| Depositing user: | Pure Administrator |
| Date Deposited: | 18 Nov 2011 16:54 |
| Last modified: | 04 Oct 2012 13:58 |
| URI: | http://strathprints.strath.ac.uk/id/eprint/36041 |
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