Strathprints Home | Open Access | Browse | Search | User area | Copyright | Help | Library Home | SUPrimo

Topical drug delivery in the eye

Wilson, Clive (2004) Topical drug delivery in the eye. Experimental Eye Research, 78 (3). pp. 737-743.

Full text not available in this repository. (Request a copy from the Strathclyde author)

Abstract

Introduction of a drug or polymer directly into the conjunctival sac should, in theory, facilitate the maximum level of efficacy. In practice, most material undergoes non-productive loss. The work of David Maurice facilitated a better understanding of drug entry by the study of probes delivered in several formulations, and by the construction of instruments to study probe distribution. This review describes research on the applications of gamma scintigraphy to follow the residence of polymers in the eye and the evaluation of the data to assess potential new materials. Finally, our progress on the construction of an ocular spectrometer to directly follow drug entry following topical administration is described.

Item type: Article
ID code: 35872
Keywords: lacrimal scintigraphy, polymers, precorneal film, drug absorption, in vivo spectrometry, Pharmacy and materia medica
Subjects: Medicine > Pharmacy and materia medica
Department: Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
Related URLs:
    Depositing user: Pure Administrator
    Date Deposited: 15 Nov 2011 14:30
    Last modified: 12 Mar 2012 11:40
    URI: http://strathprints.strath.ac.uk/id/eprint/35872

    Actions (login required)

    View Item