Picture of a sphere with binary code

Making Strathclyde research discoverable to the world...

The Strathprints institutional repository is a digital archive of University of Strathclyde research outputs. It exposes Strathclyde's world leading Open Access research to many of the world's leading resource discovery tools, and from there onto the screens of researchers around the world.

Explore Strathclyde Open Access research content

One-pot four-component reaction for the generation of pyrazoles and pyrimidines

Stonehouse, Jeffrey and Chekmarev, Dmitriy and Ivanova, Natalya and Lang, Stuart and Pairaudeau, Garry and Smith, Neal and Stocks, Michael and Sviridov, Sergey and Utkina, Lyubov (2008) One-pot four-component reaction for the generation of pyrazoles and pyrimidines. Synlett (1). pp. 100-104. ISSN 0936-5214

Full text not available in this repository. (Request a copy from the Strathclyde author)

Abstract

The palladium-catalysed four-component coupling of a halide, terminal alkyne, molybdenum hexacarbonyl and either a hydrazine or amidine has been shown to be an efficient method for the construction of highly substituted pyrazoles and pyrimidines, respectively, in a one-pot process