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The Strathprints institutional repository is a digital archive of University of Strathclyde research outputs.

Strathprints serves world leading Open Access research by the University of Strathclyde, including research by the Strathclyde Institute of Pharmacy and Biomedical Sciences (SIPBS), where research centres such as the Industrial Biotechnology Innovation Centre (IBioIC), the Cancer Research UK Formulation Unit, SeaBioTech and the Centre for Biophotonics are based.

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One-pot four-component reaction for the generation of pyrazoles and pyrimidines

Stonehouse, Jeffrey and Chekmarev, Dmitriy and Ivanova, Natalya and Lang, Stuart and Pairaudeau, Garry and Smith, Neal and Stocks, Michael and Sviridov, Sergey and Utkina, Lyubov (2008) One-pot four-component reaction for the generation of pyrazoles and pyrimidines. Synlett (1). pp. 100-104. ISSN 0936-5214

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Abstract

The palladium-catalysed four-component coupling of a halide, terminal alkyne, molybdenum hexacarbonyl and either a hydrazine or amidine has been shown to be an efficient method for the construction of highly substituted pyrazoles and pyrimidines, respectively, in a one-pot process