Zhang, Yinan and Birch, David J. S. and Chen, Yu (2011) Two-photon excited surface plasmon enhanced energy transfer between DAPI and gold nanoparticles: opportunities in intra-cellular imaging and sensing. Applied Physics Letters, 99 (10). -. ISSN 0003-6951Full text not available in this repository. (Request a copy from the Strathclyde author)
We have demonstrated energy transfer between 4'-6-Diamidino-2-phenylindole (DAPI), a commonly used DNA label, and gold nanoparticles under two-photon excitation in solution using fluorescence lifetime imaging microscopy (FLIM). With comparable size and concentration, gold nanorods (GNRs) are shown to provide more efficient energy transfer than gold nanospheres (GNSs). We attribute this transfer enhancement effect to the longitudinal surface plasmon mode of GNRs overlapping with the excitation wavelength. Energy transfer under two-photon excitation between GNRs and DAPI has also been observed in cell culture and found to be in accord with the solution phase results.
|Keywords:||biomedical optical imaging, cellular biophysics, excited states, fluorescence, gold, nanomedicine, nanoparticles, nanorods, nanosensors, surface plasmon resonance, two-photon processes, CELLS, resonance, TIC - Bionanotechnology, Solid state physics. Nanoscience|
|Subjects:||Science > Physics > Solid state physics. Nanoscience|
|Department:||Faculty of Science > Physics|
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|Depositing user:||Pure Administrator|
|Date Deposited:||28 Oct 2011 14:17|
|Last modified:||07 Dec 2013 02:45|
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