Johnston, Andrea and Florence, Alastair J. and Kennedy, Alan R. (2006) Hydrochlorothiazide N-methyl-2-pyrrolidone disolvate. Acta Crystallographica Section E: Structure Reports, 62. O5169-O5171. ISSN 1600-5368
Full text not available in this repository. (Request a copy from the Strathclyde author)Official URL: http://dx.doi.org/10.1107/S1600536806042838
Abstract
Hydrochlorothiazide forms a 1: 2 solvate with N-methylpyrrolidone (systematic name: 6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide N-methyl-2pyrrolidone disolvate), C7H8ClN3O4S2 center dot 2C(5)H(9)NO. The compound crystallizes with one hydrochlorothiazide and two solvent molecules, one of which is disordered, in the asymmetric unit. The crystal structure is isostructural with the previously reported hydrochlorothiazide N, N-dimethylacetamide disolvate.
| Item type: | Article |
|---|---|
| ID code: | 35247 |
| Keywords: | hydrochlorothiazide , disolvates, crystallization, Chemistry, Therapeutics. Pharmacology |
| Subjects: | Science > Chemistry Medicine > Therapeutics. Pharmacology |
| Department: | Faculty of Science > Pure and Applied Chemistry Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences |
| Related URLs: | |
| Depositing user: | Pure Administrator |
| Date Deposited: | 02 Nov 2011 12:28 |
| Last modified: | 04 Oct 2012 14:03 |
| URI: | http://strathprints.strath.ac.uk/id/eprint/35247 |
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