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Effect of 405 nm high-intensity narrow-spectrum light on osteoblast function

Mcdonald, Richard and Maclean, Michelle and Anderson, John and Macgregor, Scott and Grant, Mary (2011) Effect of 405 nm high-intensity narrow-spectrum light on osteoblast function. In: XII eCells & Materials Conference on Implant Infection, 2011-06-23 - 2011-06-25.

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Abstract

A significant portion of medical devices fail due to acquired infection, with infection rates after arthroplasty surgery between 1-4%, and considerably higher after revision surgery. To reduce the associated costs of infection, a new preventative method is required. High intensity narrow spectrum (HINS) 405 nm light is a new technology shown to have bactericidal effects on a range of medically important bacteria[1]. The effect of HINS-light on osteoblasts and bacteria were investigated to determine the potential of this technology to contribute to infection prevention in operating theatres, during surgery and postoperative dressing changes.