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The Strathprints institutional repository is a digital archive of University of Strathclyde research outputs. Strathprints provides access to thousands of Open Access research papers by University of Strathclyde researchers, including those from the School of Psychological Sciences & Health - but also papers by researchers based within the Faculties of Science, Engineering, Humanities & Social Sciences, and from the Strathclyde Business School.

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Scanning force microscopy of protein-patterns

Frediani, C and Allegrini, M and Ascoli, C and Connolly, P and Labardi, M and Moores, G and Arnaud, E P (1994) Scanning force microscopy of protein-patterns. Nanotechnology, 5 (2). pp. 95-100. ISSN 0957-4484

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Abstract

The development of microminiaturized biosensors requires techniques for immobilizing biomolecules on solid substrates, in an ordered fashion, and techniques for the subsequent visualization of these patterns. Scanning force microscopy (SFM) is a useful technique for visualizing ordered patterns, but it requires suitable substrates and attachment techniques. Here we present a photolithographic method which gives ordered patterns of biomolecules. Both SFM topographic and lateral force images of these patterns are shown and discussed.