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Large-scale protein topology mapping for drug design.

Wilson, John and Dufton, Mark (2011) Large-scale protein topology mapping for drug design. UNSPECIFIED. (Unpublished)

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Abstract

Large protein molecules with complex three-dimensional structures and dynamic behaviours pose a formidable challenge to humans in terms of mental assimilation, rationalisation and invention. SID technology comprises systems for analysing and displaying the structure of proteins and nucleic acids (proSID & nuSID). These systems are supported by an underlying database containing structural information. This drug discovery technology is currently the subject of negotiation between the University and an external pharmaceutical company.