Tomkinson, Nicholas C. O. and Willson, Timothy M. and Spencer, Thomas A. and Russell, Jonathon S. (1998) Efficient, stereoselective synthesis of 24(S),25-epoxycholesterol. In: 216th National Meeting of the American Chemical Society, 1998-08-23 - 1998-08-27, Boston.
Full text not available in this repository. (Request a copy from the Strathclyde author)Abstract
Efficient, stereoselective syntheses of 24(S),25-epoxycholesterol (1) have been developed starting from cholenic acid (2) or stigmasterol (3), both featuring as the key step Sharpless asym. dihydroxylation of desmosterol acetate (4). This work permits prepn. of gram quantities of 1 for further evaluation as a natural regulator of cholesterol metab., specifically, e.g., as a ligand for the LXRα nuclear receptor. [on SciFinder(R)]
| Item type: | Conference or Workshop Item (Other) |
|---|---|
| ID code: | 34221 |
| Notes: | CAPLUS AN 1998:530388(Conference; Meeting Abstract) |
| Keywords: | efficient, steroselective synthesis, 25-epoxycholesterol, Chemistry |
| Subjects: | Science > Chemistry |
| Department: | Faculty of Science > Pure and Applied Chemistry |
| Related URLs: | |
| Depositing user: | Pure Administrator |
| Date Deposited: | 15 Nov 2011 15:56 |
| Last modified: | 04 Oct 2012 17:50 |
| URI: | http://strathprints.strath.ac.uk/id/eprint/34221 |
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