Parks, Derek J. and Tomkinson, Nicholas C. O. and Villeneuve, Manon S. and Blanchard, Steven G. and Willson, Timothy M. (1998) Differential activity of rosiglitazone enantiomers at PPARγ. Bioorganic and Medicinal Chemistry Letters, 8 (24). pp. 3657-3658. ISSN 0960-894X
Full text not available in this repository. (Request a copy from the Strathclyde author)Official URL: http://dx.doi.org/10.1016/S0960-894X(98)00664-7
Abstract
Anal. of the enantiomers of rosiglitazone in a PPARγ binding assay suggests that the (S)-(-)- isomer is responsible for the antidiabetic activity.
| Item type: | Article |
|---|---|
| ID code: | 34216 |
| Notes: | M1 - Copyright (C) 2011 American Chemical Society (ACS). All Rights Reserved. CAPLUS AN 1999:50739(Journal) |
| Keywords: | rosiglitazone enantiomers , rosiglitazone , antidiabetic activity, Chemistry |
| Subjects: | Science > Chemistry |
| Department: | Faculty of Science > Pure and Applied Chemistry |
| Related URLs: | |
| Depositing user: | Pure Administrator |
| Date Deposited: | 20 Oct 2011 16:22 |
| Last modified: | 12 Mar 2012 11:35 |
| URI: | http://strathprints.strath.ac.uk/id/eprint/34216 |
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