Picture of Open Access badges

Discover Open Access research at Strathprints

It's International Open Access Week, 24-30 October 2016. This year's theme is "Open in Action" and is all about taking meaningful steps towards opening up research and scholarship. The Strathprints institutional repository is a digital archive of University of Strathclyde research outputs. Explore recent world leading Open Access research content by University of Strathclyde researchers and see how Strathclyde researchers are committing to putting "Open in Action".


Image: h_pampel, CC-BY

CHED 146-Functionalized nanoparticles as responsive nanobiosensors

Pascoe, Cherilyn and Graham, Duncan (2008) CHED 146-Functionalized nanoparticles as responsive nanobiosensors. Abstracts of papers - American Chemical Society, 236. -. ISSN 0065-7727

Full text not available in this repository. (Request a copy from the Strathclyde author)


Modern molecular diagnostics relies on a variety of different approaches. One that is increasing in popularity involves functionalised metallic nanoparticles as responsive nanobiosensors. Surface enhanced resonance Raman scatting (SERRS) use metallic nanoparticles of silver or gold to enhance the Raman scatting of the target. In this study, metallic nanoparticles are functionalized with a biomolecular probe (e.g. an antibody) to form a nanobiosensor. SERRS is achieved by attaching a reporter dye to the nanoparticle and biomolecular probe. These sensors can be used to analyze an antigen representative of a particular disease. This study focuses on the investigation of functionalized nanoparticles as responsive SERRS nanobiosensors for ultrasensitive analysis.