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Strathclyde Open Access research that creates ripples...

The Strathprints institutional repository is a digital archive of University of Strathclyde's Open Access research outputs. Strathprints provides access to thousands of research papers by University of Strathclyde researchers, including by Strathclyde physicists involved in observing gravitational waves and black hole mergers as part of the Laser Interferometer Gravitational-Wave Observatory (LIGO) - but also other internationally significant research from the Department of Physics. Discover why Strathclyde's physics research is making ripples...

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Micro-/nano-patterning of DNA and rapid readout with SERS tags

Sun, Shuqing and Thompson, David and Schmidt, Ute and Graham, Duncan and Leggett, Graham J. (2010) Micro-/nano-patterning of DNA and rapid readout with SERS tags. Chemical Communications (London), 46 (29). pp. 5292-5294. ISSN 0009-241X

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Abstract

Hybridisation of oligonucleotide micro-and nano-structures, formed using far-and near-field optical lithography, with Raman dye-labelled silver nanoparticles functionalised with complementary oligonucleotides yields striking contrast, attributed to Raman "hot-spot'' formation, and enables rapid, convenient read-out by Raman microscopy.