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Open Access research that challenges the mind...

The Strathprints institutional repository is a digital archive of University of Strathclyde research outputs. Strathprints provides access to thousands of Open Access research papers by University of Strathclyde researchers, including those from the School of Psychological Sciences & Health - but also papers by researchers based within the Faculties of Science, Engineering, Humanities & Social Sciences, and from the Strathclyde Business School.

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Micro-/nano-patterning of DNA and rapid readout with SERS tags

Sun, Shuqing and Thompson, David and Schmidt, Ute and Graham, Duncan and Leggett, Graham J. (2010) Micro-/nano-patterning of DNA and rapid readout with SERS tags. Chemical Communications (London), 46 (29). pp. 5292-5294. ISSN 0009-241X

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Abstract

Hybridisation of oligonucleotide micro-and nano-structures, formed using far-and near-field optical lithography, with Raman dye-labelled silver nanoparticles functionalised with complementary oligonucleotides yields striking contrast, attributed to Raman "hot-spot'' formation, and enables rapid, convenient read-out by Raman microscopy.