Picture of Open Access badges

Discover Open Access research at Strathprints

It's International Open Access Week, 24-30 October 2016. This year's theme is "Open in Action" and is all about taking meaningful steps towards opening up research and scholarship. The Strathprints institutional repository is a digital archive of University of Strathclyde research outputs. Explore recent world leading Open Access research content by University of Strathclyde researchers and see how Strathclyde researchers are committing to putting "Open in Action".


Image: h_pampel, CC-BY

Energy balance and its measurement in childhood disease

Reilly, John J (2008) Energy balance and its measurement in childhood disease. Pediatric Blood and Cancer, 50. pp. 452-455.

Full text not available in this repository. (Request a copy from the Strathclyde author)


Under and overweight, usually secondary to energy imbalance, are common complications of childhood chronic disease. A simple energy balance paradigm has been helpful in understanding the etiology of underweight and overweight in chronic disease, including malignant disease, particularly when measurements of total energy expenditure have been made using the doubly labeled water method. Measurements of energy intake are usually insufficiently accurate and precise to be informative, and measurements of energy expended at rest alone provide an incomplete and potentially misleading assessment of energy expenditure and the causes of energy imbalance. In some diseases, such as acute lymphoblastic leukemia, the natural history and etiology of energy imbalance are now particularly well understood. Recent improvements in our understanding of etiology should lead to improved strategies for the prevention and treatment of underweight and overweight in chronic disease. In some diseases, cachectic processes drive the development of underweight: these are partly independent of energy balance, and strategies for prevention and treatment may require approaches aimed at modifying the cachectic process rather than attempting to modify energy balance directly. Pediatr Blood Cancer