Strathprints Home | Open Access | Browse | Search | User area | Copyright | Help | Library Home | SUPrimo

Synthesis, full chemical characterisation and development of validated methods for the quantification of (±)-4′-methylmethcathinone (mephedrone) : a new "legal high"

Santali, Eman Y. and Cadogan, Anna-Karina and Daeid, Niamh Nic and Savage, Kathleen A. and Sutcliffe, Oliver B. (2011) Synthesis, full chemical characterisation and development of validated methods for the quantification of (±)-4′-methylmethcathinone (mephedrone) : a new "legal high". Journal of Pharmaceutical and Biomedical Analysis, 56 (2). pp. 246-255. ISSN 0731-7085

Full text not available in this repository. (Request a copy from the Strathclyde author)

Abstract

The recent global increase in the abuse of 4'-methylmethcathinone and related compounds has developed a requirement for full chemical characterisation of these products. In this work we present full synthetic and chemical characterisation data and supplemental information for mephedrone synthesised as both the hydrobromide and hydrochloride salt. Additionally we report the first fully validated chromatographic methods for the detection and quantitative analysis of the substance both in its pure form and in the presence of a number of common adulterants used in illicit drug manufacture.

Item type: Article
ID code: 33453
Notes: Copyright © 2011 Elsevier B.V. All rights reserved.
Keywords: Mephedrone, Cathinone, legal high, analytical profiling, HPLC, Methcathionoe , 4-Methlymethcathinone, toxicity, Chemistry, Drug Discovery, Pharmaceutical Science, Spectroscopy, Analytical Chemistry, Clinical Biochemistry
Subjects: Science > Chemistry
Department: Faculty of Science > Pure and Applied Chemistry
Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
Related URLs:
Depositing user: Pure Administrator
Date Deposited: 19 Sep 2011 10:13
Last modified: 26 Oct 2014 05:04
URI: http://strathprints.strath.ac.uk/id/eprint/33453

Actions (login required)

View Item