Winn, Philip (2008) Experimental studies of pedunculopontine functions: are they motor, sensory or integrative? Parkinsonism and Related Disorders, 14 Suppl . S194-8. ISSN 1353-8020
Full text not available in this repository. (Request a copy from the Strathclyde author)Abstract
The pedunculopontine tegmental nucleus (PPTg) is involved in Parkinson's disease and has become a therapeutic target. However, its normal functions are uncertain: are they motor, sensory or integrative? This position paper reviews PPTg structure and considers experiments designed to understand its behavioural functions. The PPTg is part of the corticostriatal architecture and, consistent with this, a core deficit following lesion is the inability to properly establish action-outcome associations. Understanding normal PPTg structure and function will provide insight into the role it has in Parkinson's disease and related disorders, and will benefit the development of surgical treatments aimed here.
| Item type: | Article |
|---|---|
| ID code: | 32776 |
| Keywords: | animals, deep brain stimulation, neural pathways, parkinson disease, pedunculopontine tegmental nucleus , Therapeutics. Pharmacology |
| Subjects: | Medicine > Therapeutics. Pharmacology |
| Department: | Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences |
| Related URLs: | |
| Depositing user: | Pure Administrator |
| Date Deposited: | 24 Aug 2011 12:46 |
| Last modified: | 04 Oct 2012 13:49 |
| URI: | http://strathprints.strath.ac.uk/id/eprint/32776 |
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