Prescott, Gerald R and Chamberlain, Luke H (2011) Regional and developmental brain expression patterns of SNAP25 splice variants. BMC Neuroscience, 12 (35).Full text not available in this repository. (Request a copy from the Strathclyde author)
SNAP25 is an essential SNARE protein for regulated exocytosis in neuronal cells. Differential splicing of the SNAP25 gene results in the expression of two transcripts, SNAP25a and SNAP25b. These splice variants differ by only 9 amino acids, and studies of their expression to date have been limited to analysis of the corresponding mRNAs. Although these studies have been highly informative, it is possible that factors such as differential turnover of the SNAP25 proteins could complicate interpretations based entirely on mRNA expression profiles.
|Keywords:||SNAP 25, SNARE protein , brain expression patterns, isoforms, Therapeutics. Pharmacology, Cellular and Molecular Neuroscience|
|Subjects:||Medicine > Therapeutics. Pharmacology|
|Department:||Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences|
|Depositing user:||Pure Administrator|
|Date Deposited:||10 Aug 2011 12:07|
|Last modified:||27 Apr 2016 17:04|