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Regional and developmental brain expression patterns of SNAP25 splice variants

Prescott, Gerald R and Chamberlain, Luke H (2011) Regional and developmental brain expression patterns of SNAP25 splice variants. BMC Neuroscience, 12 (35). p. 35.

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Abstract

SNAP25 is an essential SNARE protein for regulated exocytosis in neuronal cells. Differential splicing of the SNAP25 gene results in the expression of two transcripts, SNAP25a and SNAP25b. These splice variants differ by only 9 amino acids, and studies of their expression to date have been limited to analysis of the corresponding mRNAs. Although these studies have been highly informative, it is possible that factors such as differential turnover of the SNAP25 proteins could complicate interpretations based entirely on mRNA expression profiles.

Item type: Article
ID code: 32492
Keywords: SNAP 25, SNARE protein , brain expression patterns, isoforms, Therapeutics. Pharmacology
Subjects: Medicine > Therapeutics. Pharmacology
Department: Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
Related URLs:
    Depositing user: Pure Administrator
    Date Deposited: 10 Aug 2011 13:07
    Last modified: 12 Mar 2012 11:30
    URI: http://strathprints.strath.ac.uk/id/eprint/32492

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