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The fat controller : roles of palmitoylation in intracellular protein trafficking and targeting to membrane microdomains (Review)

Greaves, Jennifer and Prescott, Gerald R and Gorleku, Oforiwa A and Chamberlain, Luke H (2009) The fat controller : roles of palmitoylation in intracellular protein trafficking and targeting to membrane microdomains (Review). Molecular Membrane Biology, 26 (1). pp. 67-79. ISSN 1464-5203

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Abstract

The attachment of palmitic acid to the amino acid cysteine via thioester linkage (S-palmitoylation) is a common post-translational modification of eukaryotic proteins. In this review, we discuss the role of palmitoylation as a versatile protein sorting signal, regulating protein trafficking between distinct intracellular compartments and the micro-localization of proteins within membranes.

Item type: Article
ID code: 32488
Keywords: protein sorting, lipoylation, membrane microdomains, protein processing, post-translational, protein sorting signals, protein transport, proteins, palmitoylation , lipid rafts, Therapeutics. Pharmacology, Cell Biology, Molecular Biology
Subjects: Medicine > Therapeutics. Pharmacology
Department: Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
Related URLs:
    Depositing user: Pure Administrator
    Date Deposited: 10 Aug 2011 11:45
    Last modified: 05 Sep 2014 10:09
    URI: http://strathprints.strath.ac.uk/id/eprint/32488

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