Greaves, Jennifer and Prescott, Gerald R and Gorleku, Oforiwa A and Chamberlain, Luke H (2009) The fat controller : roles of palmitoylation in intracellular protein trafficking and targeting to membrane microdomains (Review). Molecular Membrane Biology, 26 (1). pp. 67-79. ISSN 1464-5203
Full text not available in this repository. (Request a copy from the Strathclyde author)Official URL: http://dx.doi.org/10.1080/09687680802620351
Abstract
The attachment of palmitic acid to the amino acid cysteine via thioester linkage (S-palmitoylation) is a common post-translational modification of eukaryotic proteins. In this review, we discuss the role of palmitoylation as a versatile protein sorting signal, regulating protein trafficking between distinct intracellular compartments and the micro-localization of proteins within membranes.
| Item type: | Article |
|---|---|
| ID code: | 32488 |
| Keywords: | protein sorting, lipoylation, membrane microdomains, protein processing, post-translational, protein sorting signals, protein transport, proteins, palmitoylation , lipid rafts, Therapeutics. Pharmacology |
| Subjects: | Medicine > Therapeutics. Pharmacology |
| Department: | Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences |
| Related URLs: | |
| Depositing user: | Pure Administrator |
| Date Deposited: | 10 Aug 2011 11:45 |
| Last modified: | 04 Oct 2012 13:49 |
| URI: | http://strathprints.strath.ac.uk/id/eprint/32488 |
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