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Imaging of the host/parasite interplay in cutaneous leishmaniasis

Millington, Owain and Myburgh, E and Mottram, Jeremy and Alexander, James (2010) Imaging of the host/parasite interplay in cutaneous leishmaniasis. Experimental Parasitology, 126 (3). pp. 310-317. ISSN 0014-4894

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Abstract

An understanding of host-parasite interplay is essential for the development of therapeutics and vaccines. Immunoparasitologists have learned a great deal from 'conventional' in vitro and in vivo approaches, but recent developments in imaging technologies have provided us (immunologists and parasitologists) with the ability to ask new and exciting questions about the dynamic nature of the parasite-immune system interface. These studies are providing us with new insights into the mechanisms involved in the initiation of a Leishmania infection and the consequent induction and regulation of the immune response. Here, we review some of the recent developments and discuss how these observations can be further developed to understand the immunology of cutaneous Leishmania infection in vivo.

Item type: Article
ID code: 32438
Keywords: Leishmania, immunology, microscopy, parasites, cutaneous leishmaniasis, Pharmacy and materia medica, Immunology, Parasitology
Subjects: Medicine > Pharmacy and materia medica
Department: Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
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Depositing user: Pure Administrator
Date Deposited: 05 Aug 2011 11:50
Last modified: 27 Mar 2014 09:29
URI: http://strathprints.strath.ac.uk/id/eprint/32438

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