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Open Access research that challenges the mind...

The Strathprints institutional repository is a digital archive of University of Strathclyde research outputs. Strathprints provides access to thousands of Open Access research papers by University of Strathclyde researchers, including those from the School of Psychological Sciences & Health - but also papers by researchers based within the Faculties of Science, Engineering, Humanities & Social Sciences, and from the Strathclyde Business School.

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Matriptase is a novel initiator of cartilage matrix degradation in osteoarthritis

Milner, J. M. and Patel, A. and Davidson, R. K. and Swingler, T. E. and Desilets, A. and Young, D. A. and Kelso, E. B. and Donell, S. T. and Cawston, T. E. and Clark, I. M. and Ferrell, W. R. and Plevin, R. and Lockhart, J. C. and Leduc, R. and Rowan, A. D. (2010) Matriptase is a novel initiator of cartilage matrix degradation in osteoarthritis. [Review]

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Abstract

Increasing evidence implicates serine proteinases in pathological tissue turnover. This study assessed the role of the transmembrane serine proteinase matriptase in cartilage destruction in osteoarthritis (OA).