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Open Access research with a real impact on health...

The Strathprints institutional repository is a digital archive of University of Strathclyde's Open Access research outputs. Strathprints provides access to thousands of Open Access research papers by Strathclyde researchers, including by researchers from the Physical Activity for Health Group based within the School of Psychological Sciences & Health. Research here seeks to better understand how and why physical activity improves health, gain a better understanding of the amount, intensity, and type of physical activity needed for health benefits, and evaluate the effect of interventions to promote physical activity.

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Matriptase is a novel initiator of cartilage matrix degradation in osteoarthritis

Milner, J. M. and Patel, A. and Davidson, R. K. and Swingler, T. E. and Desilets, A. and Young, D. A. and Kelso, E. B. and Donell, S. T. and Cawston, T. E. and Clark, I. M. and Ferrell, W. R. and Plevin, R. and Lockhart, J. C. and Leduc, R. and Rowan, A. D. (2010) Matriptase is a novel initiator of cartilage matrix degradation in osteoarthritis. [Review]

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Abstract

Increasing evidence implicates serine proteinases in pathological tissue turnover. This study assessed the role of the transmembrane serine proteinase matriptase in cartilage destruction in osteoarthritis (OA).