Henriquez, F L and Richards, T A and Roberts, F and McLeod, R and Roberts, C W (2005) The unusual mitochondrial compartment of Cryptosporidium parvum. Trends in Parasitology, 21 (2). pp. 68-74. ISSN 1471-4922
Full text not available in this repository. (Request a copy from the Strathclyde author)Abstract
Recent studies, including the Cryptosporidium parvum Genome Project, have provided evidence for a mitochondrial-derived compartment in this parasite. This organelle appears to lack a genome, and thus must be entirely dependent on nuclear-encoded proteins. Here, we review the evidence for such an organelle in C. parvum and its probable function. There is no adequate treatment for infection by this parasite and so the elucidation of the role of this organelle and the effective targeting of its functions by antimicrobial agents might provide new treatments for infection by C. parvum.
| Item type: | Article |
|---|---|
| ID code: | 31734 |
| Keywords: | plastid terminal oxidase, alternative oxidase, trichomonas-vaginalis, therapeutic implications, giardia-intestinalis, proton translocation, targeting sequences, protein importq, gene iscs, apicomplexan, Pharmacy and materia medica |
| Subjects: | Medicine > Pharmacy and materia medica |
| Department: | Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences Faculty of Science > Mathematics and Statistics |
| Related URLs: | |
| Depositing user: | Pure Administrator |
| Date Deposited: | 01 Jul 2011 16:20 |
| Last modified: | 04 Oct 2012 13:45 |
| URI: | http://strathprints.strath.ac.uk/id/eprint/31734 |
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