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The Strathprints institutional repository is a digital archive of University of Strathclyde research outputs.

Strathprints serves world leading Open Access research by the University of Strathclyde, including research by the Strathclyde Institute of Pharmacy and Biomedical Sciences (SIPBS), where research centres such as the Industrial Biotechnology Innovation Centre (IBioIC), the Cancer Research UK Formulation Unit, SeaBioTech and the Centre for Biophotonics are based.

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Human physiological and heat shock protein 72 adaptations during the initial phase of humid-heat acclimation

Marshall, Helen C. and Campbell, Samantha A. and Roberts, Craig W. and Nimmo, Myra A. (2007) Human physiological and heat shock protein 72 adaptations during the initial phase of humid-heat acclimation. Journal of Thermal Biology, 32 (6). pp. 341-348. ISSN 0306-4565

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Abstract

The timescale and integration of human whole body and cellular Hsp72 adaptations during the initial phase of human-heat acclimation were determined. Two exercise humid-heat exposures on consecutive days lowered exercise rectal temperature (P < 0.05) and heart rate (P < 0.01). Sweat rate was increased (P < 0.001) during exercise through an improved maintenance of sweating, and sweat Na+ reabsorption was enhanced (P < 0.05). These adaptations were accompanied by a reduced Hsp72 mRNA response with no change in protein level. Two prolonged, low-intensity exercise-heat bouts on consecutive days are sufficient to initiate physiological and Hsp72 mRNA adaptations, although Hsp72 protein adaptation may require a greater exercise intensity or longer acclimation period.