Marshall, Helen C. and Campbell, Samantha A. and Roberts, Craig W. and Nimmo, Myra A. (2007) Human physiological and heat shock protein 72 adaptations during the initial phase of humid-heat acclimation. Journal of Thermal Biology, 32 (6). pp. 341-348. ISSN 0306-4565
Full text not available in this repository. (Request a copy from the Strathclyde author)Abstract
The timescale and integration of human whole body and cellular Hsp72 adaptations during the initial phase of human-heat acclimation were determined. Two exercise humid-heat exposures on consecutive days lowered exercise rectal temperature (P < 0.05) and heart rate (P < 0.01). Sweat rate was increased (P < 0.001) during exercise through an improved maintenance of sweating, and sweat Na+ reabsorption was enhanced (P < 0.05). These adaptations were accompanied by a reduced Hsp72 mRNA response with no change in protein level. Two prolonged, low-intensity exercise-heat bouts on consecutive days are sufficient to initiate physiological and Hsp72 mRNA adaptations, although Hsp72 protein adaptation may require a greater exercise intensity or longer acclimation period.
| Item type: | Article |
|---|---|
| ID code: | 31723 |
| Keywords: | acclimation, heat shock protein 72, humid-heat stress, eccrine sweat gland, human-leukocytes, exercise, expression, responses, temperature, protein, plasma, HSP70, hot, Pharmacy and materia medica |
| Subjects: | Medicine > Pharmacy and materia medica |
| Department: | Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences |
| Related URLs: | |
| Depositing user: | Pure Administrator |
| Date Deposited: | 30 Jun 2011 16:30 |
| Last modified: | 12 Mar 2012 11:28 |
| URI: | http://strathprints.strath.ac.uk/id/eprint/31723 |
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