Picture of athlete cycling

Open Access research with a real impact on health...

The Strathprints institutional repository is a digital archive of University of Strathclyde's Open Access research outputs. Strathprints provides access to thousands of Open Access research papers by Strathclyde researchers, including by researchers from the Physical Activity for Health Group based within the School of Psychological Sciences & Health. Research here seeks to better understand how and why physical activity improves health, gain a better understanding of the amount, intensity, and type of physical activity needed for health benefits, and evaluate the effect of interventions to promote physical activity.

Explore open research content by Physical Activity for Health...

Depolarization of skeletal muscle cells in culture by a cardiotoxin-like basic polypeptide from the venom of the Taiwan cobra (naja naja atra)

Harvey, A L and Hayashi, K (1987) Depolarization of skeletal muscle cells in culture by a cardiotoxin-like basic polypeptide from the venom of the Taiwan cobra (naja naja atra). Toxicon, 25 (6). pp. 681-684. ISSN 0041-0101

Full text not available in this repository. Request a copy from the Strathclyde author

Abstract

A cardiotoxin-like basic polypeptide from the venom of Naja naja atra is homologous to cardiotoxins from the same venom, but much less toxic. To determine if it acts like the cardiotoxins its depolarizing ability was measured. It was about 10 times less potent than the cardiotoxins. Five amino acids are conserved in the sequences studied, on the exposed second and third loops of the toxin backbone. They may be part of the toxins' interactive site.