Harvey, A L and Hayashi, K (1987) Depolarization of skeletal muscle cells in culture by a cardiotoxin-like basic polypeptide from the venom of the Taiwan cobra (naja naja atra). Toxicon, 25 (6). pp. 681-684. ISSN 0041-0101
Full text not available in this repository. (Request a copy from the Strathclyde author)Official URL: http://dx.doi.org/10.1016/0041-0101(87)90116-4
Abstract
A cardiotoxin-like basic polypeptide from the venom of Naja naja atra is homologous to cardiotoxins from the same venom, but much less toxic. To determine if it acts like the cardiotoxins its depolarizing ability was measured. It was about 10 times less potent than the cardiotoxins. Five amino acids are conserved in the sequences studied, on the exposed second and third loops of the toxin backbone. They may be part of the toxins' interactive site.
| Item type: | Article |
|---|---|
| ID code: | 31692 |
| Keywords: | aimals, chick embryo, cobra venoms, muscles, neuromuscular depolarizing Agents, peptides |
| Subjects: | UNSPECIFIED |
| Department: | Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences |
| Related URLs: | |
| Depositing user: | Pure Administrator |
| Date Deposited: | 13 Jul 2011 09:57 |
| Last modified: | 12 Mar 2012 11:28 |
| URI: | http://strathprints.strath.ac.uk/id/eprint/31692 |
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