Picture of person typing on laptop with programming code visible on the laptop screen

World class computing and information science research at Strathclyde...

The Strathprints institutional repository is a digital archive of University of Strathclyde's Open Access research outputs. Strathprints provides access to thousands of Open Access research papers by University of Strathclyde researchers, including by researchers from the Department of Computer & Information Sciences involved in mathematically structured programming, similarity and metric search, computer security, software systems, combinatronics and digital health.

The Department also includes the iSchool Research Group, which performs leading research into socio-technical phenomena and topics such as information retrieval and information seeking behaviour.

Explore

Pharmacotherapy to improve outcomes in infrainguinal bypass graft surgery : a review of current treatment strategies

Jackson, Andrew J. and Coats, Paul and Orr, Douglas J. and Teenan, R. Paul and Wadsworth, Roger M. (2010) Pharmacotherapy to improve outcomes in infrainguinal bypass graft surgery : a review of current treatment strategies. Annals of Vascular Surgery, 24 (4). pp. 562-572. ISSN 0890-5096

Full text not available in this repository. Request a copy from the Strathclyde author

Abstract

A total of 12,000 infrainguinal bypass grafts are performed annually in the United Kingdom, with outcomes suboptimal: 20% of above-knee vein grafts require intervention by 3 years. Transatlantic Inter-Society Consensus (TASC) guidelines exist on pharmacological management of peripheral vascular disease patients, however, little is recommended regarding optimum pharmacological management following revascularization to improve graft patency. The current recommendation is that all patients are on an antiplatelet agent following bypass grafting, the only intervention with significant evidence supporting use. This article will review pharmacological strategies aimed at improving the survival of infrainguinal vein grafts and the current evidence base for their use.