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A paracetamol-morpholine adduct

Oswald, I D H and Motherwell, W D S and Parsons, S and Pulham, C R (2002) A paracetamol-morpholine adduct. Acta Crystallographica Section E: Structure Reports, 58 (Part 1). O1290-O1292. ISSN 1600-5368

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Abstract

Paracetamol [also known as acetaminophen or N-(4-hydroxyphenyl) acetamide] is an important analgesic drug that has recently been cocrystallized with a series of cyclic N- and Odonor compounds. This paper describes the formation of a paracetamol adduct with morpholine, viz. paracetamol± morpholine (1/2.5), C8H9NO22.5C4H9NO. There are ®ve morpholine molecules and two paracetamol molecules in the unit cell. The paracetamol molecules are held together by hydrogen bonding via morpholine molecules, one of which is disordered about an inversion centre.

Item type: Article
ID code: 31375
Keywords: crystals, acetaminophen , N-(4-hydroxyphenyl)acetamide , cocrystallized, paracetamol, Pharmacy and materia medica, Materials Science(all), Chemistry(all), Condensed Matter Physics
Subjects: Medicine > Pharmacy and materia medica
Department: Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
Related URLs:
    Depositing user: Pure Administrator
    Date Deposited: 13 Jul 2011 09:56
    Last modified: 05 Sep 2014 09:12
    URI: http://strathprints.strath.ac.uk/id/eprint/31375

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