Picture of a sphere with binary code

Making Strathclyde research discoverable to the world...

The Strathprints institutional repository is a digital archive of University of Strathclyde research outputs. It exposes Strathclyde's world leading Open Access research to many of the world's leading resource discovery tools, and from there onto the screens of researchers around the world.

Explore Strathclyde Open Access research content

A paracetamol-morpholine adduct

Oswald, I D H and Motherwell, W D S and Parsons, S and Pulham, C R (2002) A paracetamol-morpholine adduct. Acta Crystallographica Section E: Structure Reports, 58 (Part 1). O1290-O1292. ISSN 1600-5368

Full text not available in this repository. (Request a copy from the Strathclyde author)

Abstract

Paracetamol [also known as acetaminophen or N-(4-hydroxyphenyl) acetamide] is an important analgesic drug that has recently been cocrystallized with a series of cyclic N- and Odonor compounds. This paper describes the formation of a paracetamol adduct with morpholine, viz. paracetamol± morpholine (1/2.5), C8H9NO22.5C4H9NO. There are ®ve morpholine molecules and two paracetamol molecules in the unit cell. The paracetamol molecules are held together by hydrogen bonding via morpholine molecules, one of which is disordered about an inversion centre.