Oswald, I D H and Motherwell, W D S and Parsons, S (2004) A 1 : 1 co-crystal of quinol and pyridine. Acta Crystallographica Section E: Structure Reports, 60 (Part 11). O1967-O1969. ISSN 1600-5368
Full text not available in this repository. (Request a copy from the Strathclyde author)Abstract
A co-crystal of quinol and pyridine would be expected to form with 1:2 stoichiometry because quinol has two hydrogen-bond donors and pyridine has one hydrogen-bond acceptor which is more basic than phenolic oxygen. We report the structure of a 1:1 co-crystal, viz. quinol-pyridine (1/1), C6H6O2.C5H5N, which does not conform to this expectation. Its stability appears to imply that a combination of individually relatively weak C-H...O, C-H...pi and pi-pi stacking interactions are energetically competitive with O-H...N hydrogen bonds. Quinol molecules lie on inversion centres, while pyridine is in a general position.
| Item type: | Article |
|---|---|
| ID code: | 31363 |
| Keywords: | single-crystal X-ray study, T = 150 K, co-crystal , pyridine, quinol , Pharmacy and materia medica |
| Subjects: | Medicine > Pharmacy and materia medica |
| Department: | Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences |
| Related URLs: | |
| Depositing user: | Pure Administrator |
| Date Deposited: | 01 Jul 2011 16:26 |
| Last modified: | 12 Mar 2012 11:27 |
| URI: | http://strathprints.strath.ac.uk/id/eprint/31363 |
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