Oswald, I D H and Motherwell, W D S and Parsons, S (2004) A 1 : 1 co-crystal of quinol and pyridine. Acta Crystallographica Section E: Structure Reports, 60 (Part 1). O1967-O1969. ISSN 1600-5368Full text not available in this repository. (Request a copy from the Strathclyde author)
A co-crystal of quinol and pyridine would be expected to form with 1:2 stoichiometry because quinol has two hydrogen-bond donors and pyridine has one hydrogen-bond acceptor which is more basic than phenolic oxygen. We report the structure of a 1:1 co-crystal, viz. quinol-pyridine (1/1), C6H6O2.C5H5N, which does not conform to this expectation. Its stability appears to imply that a combination of individually relatively weak C-H...O, C-H...pi and pi-pi stacking interactions are energetically competitive with O-H...N hydrogen bonds. Quinol molecules lie on inversion centres, while pyridine is in a general position.
|Keywords:||single-crystal X-ray study, T = 150 K, co-crystal , pyridine, quinol , Pharmacy and materia medica, Materials Science(all), Chemistry(all), Condensed Matter Physics|
|Subjects:||Medicine > Pharmacy and materia medica|
|Department:||Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences|
|Depositing user:||Pure Administrator|
|Date Deposited:||01 Jul 2011 15:26|
|Last modified:||22 Mar 2017 11:25|