Metabolic sensing using fluorescence

Birch, David J.S. and Ganesan, Ashok and Karolin, Jan (2005) Metabolic sensing using fluorescence. Synthetic Metals, 155 (2). pp. 410-413. ISSN 0379-6779 (https://doi.org/10.1016/j.synthmet.2005.09.025)

Abstract

With a view to assessing the current boundaries of non-invasive sensing of metabolites we compare the photophysical properties of melanin nanoparticles in vivo, size selected in natural form from Sepia officinalis extracted from cuttlefish, and synthesised from L-dihydoxyphenylalanine (DOPA) in water pools of reverse micelles. The fluorescence emission spectra and excited state decay components correlate well with the particle size. Recent developments in optical technology are discussed in the context of the formidable challenges and opportunities for metabolic sensing presented by endogenous fluorophores.

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• Item metadata

  Item type:	Article
  ID code:	31133
  Dates:	Date Event 15 November 2005 Published
  Notes:	6th International Topical Conference on Optical Probes of Conjugated Polymers and Biosystems, Bangalore, INDIA, JAN 04-08, 2005
  Subjects:	Science > Physics
  Department:	Faculty of Science > Physics
  Depositing user:	Pure Administrator
  Date deposited:	01 Jul 2011 09:22
  Last modified:	08 Apr 2024 19:05
  URI:	https://strathprints.strath.ac.uk/id/eprint/31133