Giraud, Gerard and Wynne, Klaas (2002) Time-resolved optical Kerr-effect spectroscopy of low-frequency dynamics in Di-L-alanine, poly-L-alanine, and lysozyme in solution. Journal of Chemical Physics, 124 (41). pp. 12110-12111. ISSN 0021-9606Full text not available in this repository. (Request a copy from the Strathclyde author)
The low-frequency spectra of peptides and proteins in solution have been investigated with optical heterodyne-detected Raman-induced Kerr-effect spectroscopy. Spectra were obtained for di-L-alanine ALA(2) and poly-L-alanine (PLA) in dichloroacetic acid solution. The conformational dependence of those spectra at low frequency has been analyzed. ALA(2) displays a band centered at 50 cm-1, whereas the -helical PLA shows two shoulders at 60 and 140 cm-1. The similarity of the spectral features observed in PLA to those in water can be explained by analogous acoustic translational modes in the hydrogen network of the PLA -helix. The mostly -helical protein lysozyme in aqueous solution has also been investigated and showed significantly more structure with modes at 10, 35, 73, 106, and 164 cm-1.
|Keywords:||Kerr-effect spectroscopy, low-frequency dynamics, Di-L-alanine, poly-L-alanine, lysozyme, nanoscience, Solid state physics. Nanoscience, Physics and Astronomy(all), Physical and Theoretical Chemistry|
|Subjects:||Science > Physics > Solid state physics. Nanoscience|
|Department:||Faculty of Science > Physics|
|Depositing user:||Strathprints Administrator|
|Date Deposited:||02 Apr 2007|
|Last modified:||29 Apr 2016 07:29|