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Strathprints serves world leading Open Access research by the University of Strathclyde, including research by the Strathclyde Institute of Pharmacy and Biomedical Sciences (SIPBS), where research centres such as the Industrial Biotechnology Innovation Centre (IBioIC), the Cancer Research UK Formulation Unit, SeaBioTech and the Centre for Biophotonics are based.

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Measuring storage and loss moduli using optical tweezers: Broadband microrheology

Tassieri, Manlio and Gibson, Graham M. and Evans, R. M. L. and Yao, Alison M. and Warren, Rebecca and Padgett, Miles J. and Cooper, Jonathan M. (2010) Measuring storage and loss moduli using optical tweezers: Broadband microrheology. Physical Review E, 81 (2). 026308. ISSN 1539-3755

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Abstract

We present an experimental procedure to perform broadband microrheological measurements with optical tweezers. A generalized Langevin equation is adopted to relate the time-dependent trajectory of a particle in an imposed flow to the frequency-dependent moduli of the complex fluid. This procedure allows us to measure the material linear viscoelastic properties across the widest frequency range achievable with optical tweezers.