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The Strathprints institutional repository is a digital archive of University of Strathclyde's Open Access research outputs. Strathprints provides access to thousands of Open Access research papers by Strathclyde researchers, including by researchers from the Physical Activity for Health Group based within the School of Psychological Sciences & Health. Research here seeks to better understand how and why physical activity improves health, gain a better understanding of the amount, intensity, and type of physical activity needed for health benefits, and evaluate the effect of interventions to promote physical activity.

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Assessing the probability of detecting antimicrobial resistant Salmonella in livestock using mathematical models

Kavanagh, Kimberley and Kelly, Louise Anne and Snary, Emma and Gettinby, George (2008) Assessing the probability of detecting antimicrobial resistant Salmonella in livestock using mathematical models. In: Young Statisticians’ Meeting. Office for National Statistics, Newport. (Unpublished)

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Abstract

The extent to which farmed animals are infected with antimicrobial resistant zoonotic bacteria such as Salmonella is of concern due to the potential exposure of humans to an additional pool of resistance genes via the food chain, which may present a risk to public health. In Great Britain, monitoring the levels of antimicrobial resistant Salmonella in livestock occurs both as part of a passive surveillance system and as structured surveys. To provide insight into such surveillance activities, a probabilistic model, adapted for non perfect test sensitivity and specificity, has been developed to assess the probability of detecting resistance at the faecal, pen and farm level. Using this model, it is concluded that the probability of detecting resistant Salmonella is dependent upon the level of resistance within sample/pen/farm and the diagnostic power of the test used. The likelihood of detecting low level (e.g. emerging) resistance on individual farms was low and therefore the use of selective plating (antimicrobial present in the plate at the specified breakpoint concentration so growth confirms the presence of resistant Salmonella) is recommended. Importantly, the models provide an insight into the sampling and testing methods and could therefore be used to inform any future on-farm surveillance programmes or research projects.